The Human–Computer Interaction Institute (HCII) is a department within the School of Computer Science at Carnegie Mellon University (CMU) in Pittsburgh, Pennsylvania. It is considered one of the leading centers of human–computer interaction research, and was named one of the top ten most innovative schools in information technology by Computer World in 2008. For the past three decades, the institute has been the predominant publishing force at leading HCI venues, most notably ACM CHI, where it regularly contributes more than 10% of the papers. Research at the institute aims to understand and create technology that harmonizes with and improves human capabilities by integrating aspects of computer science, design, social science, and learning science.

HCII offers Human Computer Interaction (HCI) as an additional major for undergraduates, as well as a master's degree and PhDs in HCI. Students from various academic backgrounds come together from around the world to participate in this program. Students hold undergraduate degrees in psychology, design, and computer science, as well as many others. Students enter the program at various stages in their academic and professional careers. HCII research and educational programs span a full cycle of knowledge creation. The cycle includes research on how people work, play, and communicate within groups, organizations, and social structures. It includes the design, creation, and evaluation of technologies and tools to support human and social activities.